Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Ribosome ID:03010
C=92; O=69; E=0.40; R=172.05; rawP=2.15e-148; adjP=3.44e-147
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000177600	NA	RPLP2	ribosomal protein, large, P2	6181	ENSG00000177600
2	ENSG00000213741	NA	RPS29	ribosomal protein S29	6235	ENSG00000213741
3	ENSG00000083845	NA	RPS5	ribosomal protein S5	6193	ENSG00000083845
4	ENSG00000156482	NA	RPL30	ribosomal protein L30	6156	ENSG00000156482
5	ENSG00000198242	NA	RPL23A	ribosomal protein L23a	6147	ENSG00000198242
6	ENSG00000142676	NA	RPL11	ribosomal protein L11	6135	ENSG00000142676
7	ENSG00000063177	NA	RPL18	ribosomal protein L18	6141	ENSG00000063177
8	ENSG00000105193	NA	RPS16	ribosomal protein S16	6217	ENSG00000105193
9	ENSG00000147403	NA	RPL10	ribosomal protein L10	6134	ENSG00000147403
10	ENSG00000137154	NA	RPS6	ribosomal protein S6	6194	ENSG00000137154
11	ENSG00000171858	NA	RPS21	ribosomal protein S21	6227	ENSG00000171858
12	ENSG00000197756	NA	RPL37A	ribosomal protein L37a	6168	ENSG00000197756
13	ENSG00000231500	NA	RPS18	ribosomal protein S18	6222	ENSG00000231500
14	ENSG00000110700	NA	RPS13	ribosomal protein S13	6207	ENSG00000110700
15	ENSG00000162244	NA	RPL29	ribosomal protein L29	6159	ENSG00000162244
16	ENSG00000221983	NA	UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1	7311	ENSG00000221983
17	ENSG00000136942	NA	RPL35	ribosomal protein L35	11224	ENSG00000136942
18	ENSG00000118181	NA	RPS25	ribosomal protein S25	6230	ENSG00000118181
19	ENSG00000071082	NA	RPL31	ribosomal protein L31	6160	ENSG00000071082
20	ENSG00000172809	NA	RPL38	ribosomal protein L38	6169	ENSG00000172809
21	ENSG00000105640	NA	RPL18A	ribosomal protein L18a	6142	ENSG00000105640
22	ENSG00000177954	NA	RPS27	ribosomal protein S27	6232	ENSG00000177954
23	ENSG00000198755	NA	RPL10A	ribosomal protein L10a	4736	ENSG00000198755
24	ENSG00000170889	NA	RPS9	ribosomal protein S9	6203	ENSG00000170889
25	ENSG00000168028	NA	RPSA	ribosomal protein SA	3921	ENSG00000168028
26	ENSG00000198034	NA	RPS4X	ribosomal protein S4, X-linked	6191	ENSG00000198034
27	ENSG00000145592	NA	RPL37	ribosomal protein L37	6167	ENSG00000145592
28	ENSG00000171863	NA	RPS7	ribosomal protein S7	6201	ENSG00000171863
29	ENSG00000143947	NA	RPS27A	ribosomal protein S27a	6233	ENSG00000143947
30	ENSG00000164587	NA	RPS14	ribosomal protein S14	6208	ENSG00000164587
31	ENSG00000137818	NA	RPLP1	ribosomal protein, large, P1	6176	ENSG00000137818
32	ENSG00000188846	NA	RPL14	ribosomal protein L14	9045	ENSG00000188846
33	ENSG00000116251	NA	RPL22	ribosomal protein L22	6146	ENSG00000116251
34	ENSG00000149273	NA	RPS3	ribosomal protein S3	6188	ENSG00000149273
35	ENSG00000142937	NA	RPS8	ribosomal protein S8	6202	ENSG00000142937
36	ENSG00000008988	NA	RPS20	ribosomal protein S20	6224	ENSG00000008988
37	ENSG00000115268	NA	RPS15	ribosomal protein S15	6209	ENSG00000115268
38	ENSG00000140988	NA	RPS2	ribosomal protein S2	6187	ENSG00000140988
39	ENSG00000174748	NA	RPL15	ribosomal protein L15	6138	ENSG00000174748
40	ENSG00000122406	NA	RPL5	ribosomal protein L5	6125	ENSG00000122406
41	ENSG00000142541	NA	RPL13A	ribosomal protein L13a	23521	ENSG00000142541
42	ENSG00000109475	NA	RPL34	ribosomal protein L34	6164	ENSG00000109475
43	ENSG00000167526	NA	RPL13	ribosomal protein L13	6137	ENSG00000167526
44	ENSG00000137876	NA	RSL24D1	ribosomal L24 domain containing 1	51187	ENSG00000137876
45	ENSG00000125691	NA	RPL23	ribosomal protein L23	9349	ENSG00000125691
46	ENSG00000198918	NA	RPL39	ribosomal protein L39	6170	ENSG00000198918
47	ENSG00000142534	NA	RPS11	ribosomal protein S11	6205	ENSG00000142534
48	ENSG00000131469	NA	RPL27	ribosomal protein L27	6155	ENSG00000131469
49	ENSG00000108298	NA	RPL19	ribosomal protein L19	6143	ENSG00000108298
50	ENSG00000161970	NA	RPL26	ribosomal protein L26	6154	ENSG00000161970
51	ENSG00000165502	NA	RPL36AL	ribosomal protein L36a-like	6166	ENSG00000165502
52	ENSG00000089009	NA	RPL6	ribosomal protein L6	6128	ENSG00000089009
53	ENSG00000147604	NA	RPL7	ribosomal protein L7	6129	ENSG00000147604
54	ENSG00000161016	NA	RPL8	ribosomal protein L8	6132	ENSG00000161016
55	ENSG00000229117	NA	RPL41	ribosomal protein L41	6171	ENSG00000229117
56	ENSG00000138326	NA	RPS24	ribosomal protein S24	6229	ENSG00000138326
57	ENSG00000166441	NA	RPL27A	ribosomal protein L27a	6157	ENSG00000166441
58	ENSG00000089157	NA	RPLP0	ribosomal protein, large, P0	6175	ENSG00000089157
59	ENSG00000130255	NA	RPL36	ribosomal protein L36	25873	ENSG00000130255
60	ENSG00000145425	NA	RPS3A	ribosomal protein S3A	6189	ENSG00000145425
61	ENSG00000148303	NA	RPL7A	ribosomal protein L7a	6130	ENSG00000148303
62	ENSG00000197958	NA	RPL12	ribosomal protein L12	6136	ENSG00000197958
63	ENSG00000144713	NA	RPL32	ribosomal protein L32	6161	ENSG00000144713
64	ENSG00000108107	NA	RPL28	ribosomal protein L28	6158	ENSG00000108107
65	ENSG00000134419	NA	RPS15A	ribosomal protein S15a	6210	ENSG00000134419
66	ENSG00000105372	NA	RPS19	ribosomal protein S19	6223	ENSG00000105372
67	ENSG00000112306	NA	RPS12	ribosomal protein S12	6206	ENSG00000112306
68	ENSG00000114391	NA	RPL24	ribosomal protein L24	6152	ENSG00000114391
69	ENSG00000174444	NA	RPL4	ribosomal protein L4	6124	ENSG00000174444

Database:KEGG pathway Name:Spliceosome ID:03040
C=127; O=6; E=0.55; R=10.84; rawP=2.11e-05; adjP=0.0002
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135486	NA	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	3178	ENSG00000135486
2	ENSG00000139343	NA	SNRPF	small nuclear ribonucleoprotein polypeptide F	6636	ENSG00000139343
3	ENSG00000171960	NA	PPIH	peptidylprolyl isomerase H (cyclophilin H)	10465	ENSG00000171960
4	ENSG00000182004	NA	SNRPE	small nuclear ribonucleoprotein polypeptide E	6635	ENSG00000182004
5	ENSG00000125743	NA	SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	6633	ENSG00000125743
6	ENSG00000130332	NA	LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	51690	ENSG00000130332

Database:KEGG pathway Name:Wnt signaling pathway ID:04310
C=150; O=4; E=0.65; R=6.12; rawP=0.0043; adjP=0.0152
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000204435	NA	CSNK2B	casein kinase 2, beta polypeptide	1460	ENSG00000204435 ENSG00000263020
2	ENSG00000174804	NA	FZD4	frizzled family receptor 4	8322	ENSG00000174804
3	ENSG00000100888	NA	CHD8	chromodomain helicase DNA binding protein 8	57680	ENSG00000100888
4	ENSG00000104290	NA	FZD3	frizzled family receptor 3	7976	ENSG00000104290

Database:KEGG pathway Name:RNA degradation ID:03018
C=71; O=3; E=0.31; R=9.69; rawP=0.0037; adjP=0.0152
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000178896	NA	EXOSC4	exosome component 4	54512	ENSG00000178896
2	ENSG00000171311	NA	EXOSC1	exosome component 1	51013	ENSG00000171311
3	ENSG00000130332	NA	LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	51690	ENSG00000130332

Database:KEGG pathway Name:Purine metabolism ID:00230
C=162; O=4; E=0.71; R=5.66; rawP=0.0057; adjP=0.0152
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000178035	NA	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	3615	ENSG00000178035
2	ENSG00000143774	NA	GUK1	guanylate kinase 1	2987	ENSG00000143774
3	ENSG00000159899	NA	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	4882	ENSG00000159899
4	ENSG00000116981	NA	NT5C1A	5'-nucleotidase, cytosolic IA	84618	ENSG00000116981

Database:KEGG pathway Name:Ribosome biogenesis in eukaryotes ID:03008
C=80; O=3; E=0.35; R=8.60; rawP=0.0052; adjP=0.0152
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000115368	NA	WDR75	WD repeat domain 75	84128	ENSG00000115368
2	ENSG00000204435	NA	CSNK2B	casein kinase 2, beta polypeptide	1460	ENSG00000204435 ENSG00000263020
3	ENSG00000105202	NA	FBL	fibrillarin	2091	ENSG00000105202

Database:KEGG pathway Name:Primary immunodeficiency ID:05340
C=35; O=2; E=0.15; R=13.11; rawP=0.0102; adjP=0.0233
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000143390	NA	RFX5	regulatory factor X, 5 (influences HLA class II expression)	5993	ENSG00000143390
2	ENSG00000076248	NA	UNG	uracil-DNA glycosylase	7374	ENSG00000076248

Database:KEGG pathway Name:Basal cell carcinoma ID:05217
C=55; O=2; E=0.24; R=8.34; rawP=0.0241; adjP=0.0428
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000174804	NA	FZD4	frizzled family receptor 4	8322	ENSG00000174804
2	ENSG00000104290	NA	FZD3	frizzled family receptor 3	7976	ENSG00000104290

Database:KEGG pathway Name:Drug metabolism - other enzymes ID:00983
C=52; O=2; E=0.23; R=8.82; rawP=0.0217; adjP=0.0428
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000178035	NA	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	3615	ENSG00000178035
2	ENSG00000198848	NA	CES1	carboxylesterase 1	1066	ENSG00000198848

Database:KEGG pathway Name:Melanogenesis ID:04916
C=101; O=2; E=0.44; R=4.54; rawP=0.0721; adjP=0.1154
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000174804	NA	FZD4	frizzled family receptor 4	8322	ENSG00000174804
2	ENSG00000104290	NA	FZD3	frizzled family receptor 3	7976	ENSG00000104290

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).